Wilm's tumor vs Neuroblastoma
Wilm’s tumor MC renal tumor of childhood Patients present under 5 years of age Increased incidence in sporadic aniridia, hemihypertrophy, Beckwith-Wiedemann syndrome, Denys-Drash syndrome, horseshoe kidney & with a family history C/F – Asymptomatic mass; however abdominal pain, hematuria, fever & hypotension secondary to renal ischemia may occur Bilateral synchronous tumors occur in 5-10% of patients USG demonstrates a large heterogenous mass arising from the kidney containing multiple low-echogenicity areas of hemorrhage or necrosis CT demonstrates the ‘claw sign’ with renal parenchyma stretched around the mass, confirming its renal origin Neuroblastoma MC extracranial solid malignant tumor in children Most children present <5 years of age Parents may detect a palpable abdominal mass Most patients have elevated urinary catecholamine levels USG – Demonstrates a hyperechoic mass in the adrenal or central retroperitoneum, often with flecks of calcifi...